當嚙齒動物在白色隔間時,可以按下按鈕激活計時器,規(guī)定在預(yù)設(shè)的延遲后開門。門開啟時啟用了延遲計時器,它在動物穿過后停止,延遲時間以0.1 s 顯示。為了防止動物因為關(guān)門感到不安或受到傷害,在穿過一秒鐘后,門就會關(guān)上。
參考文獻:
Papers which quote Ugo Basile P.A. Test (step-through)
C.I. Navarro-Francés et alia: “Influence of trait anxiety on the effects of acute stress on learning and retention of the passive avoidance task in male and female mice" Behav.Processes 105: 6-14, 2014
L. Zvejniece et alia: “The cognition-enhancing activity of E1R, a novel pos-itive allosteric modulator of sigma-1 receptors" Br. J. Pharmacol. 171(3): 761-771, 2014
R.W. Flint et alia: “NMDA receptor antagonism with MK-801 impairs consolidation and reconsolidation of passive avoidance conditioning in adolescent rats: Evidence for a state dependent reconsolidation effect" Neurobiology of Learning and Memory 101: 114-119, 2013
G. Telegdy et alia: “The action of kisspeptin-13 on passive avoidance learning in mice. Involvement of transmitters"Behav. Brain Res. 243: 2013
V. Capurro et alia: “Pharmacological Characterization of Memoquin, a Multi-Target Compound for the Treatment of Alzheimer’s Disease" PLoS ONE 8(2): e56870, 2013
J. Michaud et alia: “Hematopoietic MyD88-adaptor Protein Acts as a Natural Defense Mechanism for Cognitive Deficits in Alzheimer’s Disease" Stem Cell Reviews and Reports 8 (3): 898-904, 2012